Garribba L, Santaguida S, The Dynamic Instability of the Aneuploid Genome, Front Cell Dev Biol. 2022 Feb 21;10:838928

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Hiiragi T, Gladfelter AS, Miguel-Aliaga I, Coller HA, Lau OS, McBride HM, Aoki K, Linkermann A, Santaguida S, Wasteneys G, Rivron NC, Shahbazi MN, Ebisuya M, Lancaster MA, 20 years of Developmental Cell: Looking forward, Dev Cell. 2021 Dec 6;56(23):3185-3191

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Santaguida S, Mapelli M, Crotonylation directs the spindle, Nat Chem Biol. 2021 Dec;17(12):1217-1218

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 Alcalay M, Jereczek-Fossa BA, Pepa M, Volpe S, Zaffaroni M, Fiore F, Marvaso G, Pravettoni G, Curigliano G, Santaguida S, Pelicci PG, Biomedical omics: first insights of a new MSc degree of the University of Milan, Tumori 2022 Feb;108(1):6-11

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Ippolito MR, Martis V, Martin S, Tijhuis AE, Hong C, Wardenaar R, Dumont M, Zerbib J, Spierings DCJ, Fachinetti D, Ben-David U, Foijer F, Santaguida S, Gene copy-number changes and chromosomal instability induced by aneuploidy confer resistance to chemotherapy, Developmental Cell, 2021

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Wang RW, Viganò S, Ben-David U, Amon, Santaguida S, Aneuploid senescent cells activate NF-kB to promote their immune clearance, EMBO Reports, 2021

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Klionsky DJ et al., Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition), Autophagy 2021 Jan;17(1):1-382

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Cohen-Sharir Y, McFarland JM, Abdusamad M, Marquis C,Bernhard SV, Kazachkova M, Tang H, Ippolito MR, Laue K, Zerbib J, Malaby HLH, Jones A, Stautmeister LM, Bockaj I, Wardenaar R, Lyons N, Nagaraja A, Bass AJ, Spierings DCJ, Foijer F, Beroukhim R, Santaguida S, Golub TR, Stumpff J, Storchová Z, Ben-David U, Aneuploidy renders cancer cells vulnerable to mitotic checkpoint inhibition, Nature 2021 Feb;590(7846):486-491

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Martin S, Santaguida S, Understanding Complexity of Cancer Genomes: Lessons from Errors, Developmental Cell 2020 Volume 53 Issue 5 p493-618

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Brennan CM, Vaites LP, Wells JN, Santaguida S, Paulo JA, Storchova Z, Harper JW, Marsh JA, Amon A, Protein aggregation mediates stoichiometry of protein complexes in aneuploid cells, Genes Dev. 2019 Jun 13 ​

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Wang RW, MacDuffie E, Santaguida S, Generation and Isolation of Cell Cycle-arrested Cells with Complex Karyotypes, J. Vis. Exp. 2018 (134), e57215 

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Tang YC, Yuwen H, Wang K, Bruno PM, Bullock K, Deik AA, Santaguida S, Trakala M, Pfau SJ, Zhong N, Huang T, Wang L, Clish CB, Hemann MT, Amon A, Aneuploid cell survival relies upon sphingolipid homeostasis, Cancer Res. 2017 Oct 1;77(19):5272-5286

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Santaguida S, Richardson A, Iyer DR, M’Saad O, Zasadil L, Knouse KA, Wong Y, Rhind N, Desai A, Amon A, Chromosome mis-segregation generates cell cycle-arrested cells with complex karyotypes that are eliminated by the immune system, Developmental Cell 2017 Jun 19;41(6):638-651 

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Dodgson SE, Santaguida S, Kim S, Sheltzer J, Amon A, The pleiotropic deubiquitinase Ubp3 confers aneuploidy tolerance, Genes and Development 2016 Oct 15;30(20):2259-2271

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Loponte S, Segré CV, Senese S, Miccolo C, Santaguida S, Deflorian G, Citro S, Mattoscio D, Pisati F, Moser MA, Visintin R, Seiser C, Chiocca S, Dynamic phosphorylation of Histone Deacetylase 1 by Aurora kinases during mitosis regulates zebrafish embryos development, Sci Rep. 2016 Jul 26;6:30213

 

Segre CV, Senese S, Loponte S, Santaguida S, Soffientini P, Grigorean G, Cinquanta M, Ossolengo G, Seiser C, Chiocca S, A monoclonal antibody specific for prophase phosphorylation of Histone Deacetylase 1: a readout for early mitotic cells, MAbs. 2016;8(1):37-42

 

Klionsky DJ et al., Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition), Autophagy. 2016;12(1):1-222

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Santaguida S, Vasile E, White E, Amon A, Aneuploidy-induced cellular stresses limit autophagic degradation, Genes and Development 2015 Oct 1;29(19):2010-21

 

Santaguida S and Amon A, Aneuploidy triggers a TFEB-mediated lysosomal stress response, Autophagy. 2015;11(12):2383-4

 

Santaguida S and Amon A, Short and long-term effects of chromosome mis-segregation and aneuploidy, Nat Rev Mol Cell Biol. 2015 Aug;16(8):473-85

 

De Antoni A, Maffini S, Knapp S, Musacchio A, Santaguida S, A small-molecule inhibitor of Haspin alters the kinetochore functions of Aurora B, J Cell Biol. 2012 Oct 15;199(2):269-84

 

Elkins JM, Santaguida S, Musacchio A, Knapp S, Crystal structure of human aurora B in complex with INCENP and VX-680, J Med Chem. 2012 Sep 13;55(17):7841-8

 

Krenn V, Wehenkel A, Li X, Santaguida S, Musacchio A, Structural analysis reveals features of the spindle checkpoint kinase Bub1-kinetochore subunit Knl1 interaction, J Cell Biol. 2012 Feb 20;196(4):451-67

 

Kwiatkowski N, Deng X, Wang J, Tan L, Villa F, Santaguida S, Huang HC, Mitchison T, Musacchio A, Gray N, Selective aurora kinase inhibitors identified using a taxol-induced checkpoint sensitivity screen, ACS Chem Biol. 2012 Jan 20;7(1):185-96

 

Varetti G, Guida C, Santaguida S, Chiroli E, Musacchio A, Homeostatic control of mitotic arrest, Mol Cell. 2011 Dec 9;44(5):710-20

 

Balzano D, Santaguida S, Musacchio A, Villa F, A general framework for inhibitor resistance in protein kinases, Chem Biol. 2011 Aug 26;18(8):966-75

 

Santaguida S, Vernieri C, Villa F, Ciliberto A, Musacchio A, Evidence that Aurora B is implicated in spindle checkpoint signalling independently of error correction, EMBO J. 2011 Apr 20;30(8):1508-19

 

Petrovic A, Pasqualato S, Dube P, Krenn V, Santaguida S, Cittaro D, Monzani S, Massimiliano L, Keller J, Tarricone A, Maiolica A, Stark H, Musacchio A, The MIS12 complex is a protein interaction hub for outer kinetochore assembly, J Cell Biol. 2010 Sep 6;190(5):835-52

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Hewitt L, Tighe A, Santaguida S, White AM, Jones CD, Musacchio A, Green S, Taylor SS, Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1-C-Mad2 core complex, J Cell Biol. 2010 Jul 12;190(1):25-34

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Screpanti E, Santaguida S, Nguygen T, Silvestri R, Gussio R, Musacchio A, Hamel E, De Wulf P, A screen for kinetochore-microtubule interaction inhibitors identifies novel antitubulin compounds, PLoS One. 2010 Jul 15;5(7):e11603

 

Santaguida S, Tighe A, D'Alise AM, Taylor SS, Musacchio A, Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor Reversine, J Cell Biol. 2010 Jul 12;190(1):73-87

 

Çivril F, Wehenkel A, Giorni FM, Santaguida S, Di Fonzo A, Grigorean G, Ciccarelli FD, Musacchio A, Structural analysis of the RZZ complex reveals common ancestry with multisubunit vesicle tethering machinery, Structure 2010 May 12;18(5):616-26 

 

Santaguida S and Musacchio A, The life and miracles of kinetochores, EMBO J. 2009 Sep 2;28(17):2511-31

 

Airoldi L, Magagnotti C, Iannuzzi AR, Pastorelli R, Colombi A, Santaguida S, Chiabrando C, Schiarea S and Fanelli R, Effects of smoking on the human urinary proteome, Biochem Biophys Res Commun. 2009 Apr 10;381(3):397-402

 

Demoe JR, Santaguida S, Daum JR, Musacchio A, Gorbsky GJ, A High Throughput, Whole Cell Screen for Small Molecule Inhibitors of the Mitotic Spindle Checkpoint, Cancer Res 2009 Feb; 69: (4)

 

Amabile G, D'Alise AM, Iovino M, Jones P, Santaguida S, Musacchio A, Taylor SS, Cortese R, The Aurora-B-kinase activity is required for the maintenance of the differentiated state of murine myoblasts, Cell Death Differ. 2009 Feb;16(2):321-30

 

Ciferri C, Pasqualato S, Screpanti E, Varetti G, Santaguida S, Dos Reis G, Maiolica A, Polka J, De Luca JG, De Wulf P, Salek M, Rappsilber J, Moores CA, Salmon ED, Musacchio A, Implications for Kinetochore-Microtubule Attachment from the Structure of an Engineered Ndc80 Complex, Cell. 2008 May 2;133(3):427-39

 

Trincavelli M, Cuboni S, Montali M, Santaguida S, Lucacchini A, Martini C, Norepinephrine-mediated Regulation of 5HT(1) Receptor Functioning in Human Platelets, Neurochem Res. 2008 Jul;33(7):1292-300 

 

Mapelli M, Massimiliano L, Santaguida S, Musacchio A, The Mad2 Conformational Dimer: Structure and Implications for the Spindle Assembly Checkpoint, Cell 2007 Nov 16;131(4):730-43

 

Bassanini S, Hallene KL, Battaglia G, Finardi A, Santaguida S, Cipolla M and Janigro D, Early cerebrovascular and parenchymal events following prenatal exposure to the putative neurotoxin methylazoxymethanol, Neurobiology of Disease 2007 May; 26 (2): 481-495

 

Hallene KL, Oby E, Lee BL, Santaguida S, Bassanini S, Cipolla M, Marchi N, Hossain M, Battaglia G, Janigro D, Pre-natal exposure to Thalidomide, altered vasculogenesis, and cns malformations, Neuroscience 2006 Sep 29;142(1):267-83

 

Santaguida S, Janigro D, Hossain M, Oby E, Rapp E, Cucullo L, Side by side comparison between dynamic versus static models of blood-brain barrier in vitro: a permeability study, Brain Research, 2006 Sep 13;1109(1):1-13