Selected publications - Complete list available here
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Selected publications
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Ippolito MR, Martis V, Martin S, Tijhuis AE, Hong C, Wardenaar R, Dumont M, Zerbib J, Spierings DCJ, Fachinetti D, Ben-David U, Foijer F, Santaguida S*, Gene copy-number changes and chromosomal instability induced by aneuploidy confer resistance to chemotherapy, Developmental Cell, 2021, (*corresponding author)
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Wang RW, Viganò S, Ben-David U, Amon, Santaguida S*, Aneuploid senescent cells activate NF-kB to promote their immune clearance, EMBO Reports, 2021, (*corresponding author)

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Martin S, Santaguida S*, Understanding Complexity of Cancer Genomes: Lessons from Errors, Developmental Cell 2020 Volume 53 Issue 5 p493-618 (*corresponding author)

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Wang RW, MacDuffie E, Santaguida S*, Generation and Isolation of Cell Cycle-arrested Cells with Complex Karyotypes, J. Vis. Exp. 2018 (134), e57215, doi:10.3791/57215 (*corresponding author)

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Santaguida S*, Richardson A, Iyer DR, M’Saad O, Zasadil L, Knouse KA, Wong Y, Rhind N, Desai A, Amon A*, Chromosome mis-segregation generates cell cycle-arrested cells with complex karyotypes that are eliminated by the immune system, Developmental Cell 2017 Jun 19;41(6):638-651 (* corresponding authors)

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Santaguida S and Amon A, Aneuploidy triggers a TFEB-mediated lysosomal stress response, Autophagy 2015; 11(12):2383-4
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Santaguida S and Amon A, Short and long-term effects of chromosome mis-segregation and aneuploidy, Nat Rev Mol Cell Biol 2015 Aug;16(8):473-85 Review article



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Santaguida S, Vasile E, White E, Amon A, Aneuploidy-induced cellular stresses limit autophagic degradation, Genes and Development 2015 Oct 1;29(19):2010-21
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De Antoni A, Maffini S, Knapp S, Musacchio A*, Santaguida S*, A small-molecule inhibitor of Haspin alters the kinetochore functions of Aurora B, J Cell Biol. 2012 Oct 15;199(2):269-84 (* corresponding authors)

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Santaguida S, Vernieri C, Villa F, Ciliberto A, Musacchio A, Evidence that Aurora B is implicated in spindle checkpoint signalling independently of error correction, EMBO J. 2011 Apr 20;30(8):1508-19

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Santaguida S, Tighe A, D'Alise AM, Taylor SS, Musacchio A, Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor Reversine, J Cell Biol. 2010 Jul 12;190(1):73-87

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Santaguida S and Musacchio A, The life and miracles of kinetochores, EMBO J. 2009 Sep 2;28(17):2511-31 Review article
